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doi: 10.3390/nu14061292 22

Reapply every 23 hours, especially after sweating or washing face

[6] [25] At levels only slightly below normal, deficiency can result in fatigue, headaches, feeling faint, rapid breathing, pale skin, numbness or tingling, poor appetite, heartburn, poor balance, difficulty walking, poor reflexes, blurred vision, memory problems, depression, irritability, inattention, cognitive decline, dementia, and even psychosis

Oxidative Medicine and Cellular Longevity , 2019, 6548742

It was first discovered in the stomach of pigs in 1989 by Professor Stanislaw Burzynska and his team at the Institute of Physiology in Poland