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CAGE transcriptome analysis reveals BCL2A1 upregulation in FLT3-ITD/D835 dual mutated AML cells harboring complex co-mutations

Some patients have required drug discontinuation due to hyperglycemia or exacerbation of diabetes

Similarly, in breast cancer, LOH at this locus occurred in approximately 36% of breast cancer tissues, and GPx1 with a leucine-containing allele exhibited lower GPx1 activities in response to stimulation than GPx1 a proline-containing allele [88]

A previous history of vitiligo can also make a patient more vulnerable to a drug-induced extension of their pigment loss

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