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Hydration: Keep fluids up, particularly while titrating, when GI effects peak

Semaglutide was added to WADA monitoring because of emerging evidence suggesting athletes may use it for body composition changes, specifically fat loss, that could confer competitive advantages in weight-sensitive sports

This is called hormesis

In Alzheimers disease (AD), reductions in glucose uptake and utilization, deficits in glucose transporter 1 (GLUT1/GLUT3), impaired pyruvate dehydrogenase and -ketoglutarate dehydrogenase activity, and stress-activated AMP-activated protein kinase (AMPK) signaling converge on an energy-deficient neural milieu that precedes clinical symptoms by years (Connolly et al., 2019

Neurological recovery from B12 deficiency typically takes months, though some patients report reduced symptoms within weeks of starting treatment