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A 2020 meta-analysis in Clinical Nutrition ESPEN (Asbaghi et al.) pooled 12 randomized controlled trials and found that oral berberine reduced body weight by 2.07 kg and BMI by 0.47 kg/m2 versus control
It is produced naturally in humans, with the greatest amounts being found in muscles, the brain and in the testicles
Ligament Repair Experimental ligament transection models showed: Increased fibroblast migration Improved structural alignment Faster recovery timelines Reference: Staresinic et al., 2003 3
10:e020734
Athletes subject to anti-doping testing should be aware that these compounds may be detectable and could result in sanctions
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