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10.1186/s12931-021-01641-y Summary Keywords methotrexate, modified citrus pectin, galectin-3, hepatotoxicity, lung toxicity Citation Ismail R, Habib HA, Anter AF, Amin A and Heeba GH (2025) Modified citrus pectin ameliorates methotrexate-induced hepatic and pulmonary toxicity: role of Nrf2, galectin-3/TLR-4/NF-B/TNF- and TGF- signaling pathways