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The rectum has a more neutral pH and is not as acidic as the stomach, which makes this area much better for EDTA absorption because it is not buffered and has a neutral pH, unlike the stomach

For each analysis, the statistical test used and n for each group are found in Supplemental Tables 2, 3, or 5

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Novo Nordisk filed an NDA with the FDA on 18 December 2025 for CagriSema, the fixed-dose cagrilintide/semaglutide combination, but that submission covers the combination product and is still under review it is not an approval of cagrilintide on its own

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