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Situation 4: Reconstituted vials where you're not confident in the final concentration If you reconstituted a powder vial and didn't measure the bacteriostatic water precisely (for example, you eyeballed "about 2 mL" instead of using a syringe to measure exactly 2.00 mL), your final concentration is unknown

His HbA1c gradually rose to 13% last year

Dandona P, Mathieu C, Phillip M et al (2018) Efficacy and safety of dapagliflozin in patients with inadequately controlled type 1 diabetes: the DEPICT-1 52-week study

avoid placing the vial in the coldest part or freezer compartment

Both deliver the same active peptide, but the injection technique differs slightly between pen and syringe