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This is the glucose-dependent part of the mechanism
Nitanai Y, Satow Y, Adachi H, Tsujimoto M: Crystal structure of human renal dipeptidase involved in beta-lactam hydrolysis
A distinct nonclassical inflammasome pathway is triggered by direct binding of lipopolysaccharide (LPS) to caspase 11 (CASP11 in humans) or caspase 4/5 (CASP4/5 in mice), resulting in GSDMD cleavage [139]
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