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Nworu CS, Okoye EL, Ezeifeka GO, Esimone CO

Subjects received an 80 mg/kg dose of one APAP formulation, followed by a washout period and subsequent administration of the second 80 mg/kg formulation of APAP

The amount of cagrilintide is unchanged

Week 1: Dose: 50mcg Frequency: Once, on a night when you can sleep in the next morning Timing: 2-3 hours before intended sleep Purpose: Assess basic tolerance and response Week 2: Dose: 75-100mcg Frequency: 2-3 times during the week Timing: 1-2 hours before bed Purpose: Establish baseline effective dose During this assessment phase, track sleep quality subjectively and, if possible, with a wearable device that measures sleep stages

Wrd substancji pomocniczych uytych przy produkcji tego wyrobu medycznego wyrniamy: sl sodow kwasu salkaprozowego, powidon K90, celuloz mikrokrystaliczn, magnezu stearynian