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Average Weight Loss in the Orforglipron phase 3 ATTAIN-1 Trial Across the 72-week study period, participants: Lost up to 15% of their body weight at the highest dose At 36 mg: 54.6% lost 10%, 36.0% lost 15%, 18.4% lost 20% body weight (all higher than placebo)

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Hold stretch for 30-60 seconds Repeat

Tracking your doses across switches If you do choose to alternate, meticulous record-keeping becomes essential

Generally, no major problems happen, but tell your provider if you have a history of pancreatitis, certain thyroid cancers, severely low blood sugar, allergies, or certain kidney problems