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It is supplied as a lyophilized powder for in vitro coordination-chemistry and biochemical assay work, including UV-Vis and circular dichroism metal-binding studies, potentiometric determination of stability constants, copper-dependent oxidoreductase assays, and use as a reference standard for reversed-phase HPLC, LC-MS, and ICP-MS copper determination

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3a, b) 34 , we found periodic oscillations in both NAD and NADP redox states (Fig