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One of the limitations in this study was that blood glucose and eGFR levels were not adjusted for, while poor glycemic control and kidney dysfunction were found to be associated with increased risk of AF in patients with type 2 diabetes
The science on this is overwhelming
287 In the SUMMIT trial, tirzepatide showed a significant reduction in heart failure events in people with HFpEF but results should be interpreted with caution due to small event numbers
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And nitric oxide synthases (NOS) metabolize L-arginine to nitric oxide (NO), a molecule with dual roles in fibrosis
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