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Indeed, G6PD-deficient monocytes exhibit decreased inflammasome responsiveness to LPS, including poor induction of pro-interleukin-1 (IL-1), which has been linked to insufficient NADPH oxidase production of ROS and impaired intracellular bacterial killing (18)
Patients should be educated on recognizing serious side effects and promptly report any unusual or severe reactions during treatment
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Triggering oxidative stress , producing free radicals that inflame tissues
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