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What This Means for You as a Patient If any of the above describes a problem you are working on, the right next step is the same as it always is

Pinch the skin, insert at a 45-degree angle, inject slowly, and hold for 5 seconds before withdrawing

GI side effects may temporarily increase during the transition because tirzepatide adds GIP receptor activation

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The lack of intrinsic factor is most commonly due to autoimmune gastritis, which causes an autoimmune attack on the parietal cells that create it in the stomach