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This study aims to explore the relationship between endothelial dysfunction in HFpEF and the mechanisms of action of GLP-1R agonists, highlighting their potential therapeutic benefits

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For comparisons B and C, ORA was performed using the GOBP database 92 (release 2023) and the Reactome Pathway Knowledgebase 93 (release 2022) to identify over-represented pathways in the upregulated gene sets (padj 0.05 and padj 0.01, respectively)

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