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One study that utilized the Ins2 AKITA mouse model of type 1 diabetes showed no appreciable difference in BBB integrity, as compared to wildtype animals (Me et al., 2018)
Sources BPC-157 dosage guide 2026 (Peptides Insider): BPC-157 dosage protocols (PeptideWiki): BPC-157 dosing, reconstitution, safety 2026: Sikiric P, et al
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Notably, patients participating in the trial maintained the weight loss for several months after the last injection
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