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Moreover, oral peptides come with a catch: they require much higher quantities of active ingredient than injectables to achieve similar efficacy
However, due to its low solubility in physiological pH conditions, the oral bioavailability of RN104 is suboptimal (Silva et al., 2020)
The cost of independent testing is minimal compared to the cost of a compromised study
Wegovy is also approved to lower body weight in people with obesity (including adolescents age 12 and older), or adults who are overweight and have at least one weight-related condition such as high blood pressure, high cholesterol, or Type 2 diabetes
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