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High-dose B12, particularly intramuscular injections delivering 1,000 micrograms or more, appears more likely to trigger acne than standard dietary intake or lower-dose oral supplements

In SURMOUNT-1, at the 15 mg dose over 72 weeks, 91% of participants lost at least 5% of their body weight, 83.5% lost at least 10%, 70.6% lost at least 15%, and 56.7% lost at least 20%

Volume values characterize the mean volume of the circular area centered around the foveola, corresponding to the 6 mm ring of the circular grid defined by the Early Treatment Diabetic Retinopathy Study [23]

ClinicalTrials.gov Identifier: NCT05929066

Qin et al., 2018)