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A 2018 review found that in 11 of 14 studies, metformin showed a greater reduction in weight and BMI when compared to placebo
Cost accounts for some of that - but studies looking at the drivers of early discontinuation consistently identify side effect intolerance and lack of behavioral support as factors independent of cost
GLP-1RA Use Patterns and Discontinuation Rates The study included 201,136 incident sulfonylurea users and 132,551 incident GLP-1RA users, with a median follow-up of three years
The full titration takes about 4-5 months, so results develop more gradually than with Contrave but ultimately exceed what Contrave achieves
We empower employers to customize their approach to weight management with: Our unique step-down strategy enables employees to achieve long-term success without depending on GLP-1s indefinitely
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