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Summary While GLP-1 receptor agonists offer some benefits in managing Type 2 diabetes and obesity, they come with notable drawbacks, including dependency on medication and a range of side effects, from gastrointestinal discomfort to severe adverse events like thyroid tumors and pancreatitis
All dosing decisions, including whether a patient advances toward a Retatrutide 12mg dose, are made by a licensed provider on a case-by-case basis
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Variables such as advanced age, poor initial neurological state, large hematoma volume, and intraventricular extension are independent predictors of poor outcomes following spontaneous ICH 5,6,7,8
This compares favorably to semaglutide 2.4 mg, which reduced hepatic fat by approximately 40% in the NASH-CRN substudy of STEP-1
