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To target E2 to -cells without the undesirable effects of general estrogen therapy, we created fusion peptides combining active or inactive glucagon-like peptide-1 (GLP-1) and E2 in a single molecule (aGLP1-E2 and iGLP1-E2 respectively)
The observed increase in oxytocin receptor expression in the anterior cingulate cortex of MIA mice suggests a potential neurobiological mechanism underlying these effects [1]
Concomitant medications may also influence response
Inzucchi SE, Iliev H, Pfarr E, Zinman B (2018) Empagliflozin and assessment of lower-limb amputations in the EMPA-REG OUTCOME Trial
Prescribing Information Ozempic, WeGovy, Saxenda and Victoza are registered trademarks of Novo Nordisk
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