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That makes supplier transparency, third-party HPLC purity confirmation, and lot-specific certificates non-negotiable for any research-context sourcing
Nature Chemical Biology
The liver can store the vitamin for a long time, so it may take a few years for deficiency and symptoms to develop
Individuals with Poor Absorption: People with low stomach acid, or those who have had certain surgeries (like gastric bypass), may struggle to absorb B12 from food and would benefit from injections
Other Drugs : Vitamin B12 can interact with other drugs, such as folic acid, affecting their efficacy or increasing the risk of side effects
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