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The FDA has issued a determination that the semaglutide injection product shortage is resolved (February 21, 2025)

GLP-1RAs and heart failure The prevalence of left ventricular ejection fraction (LVEF)-preserved heart failure continues to increase

Interplay between GLP-1 Signaling and Muscle Metabolism GLP-1RAs modulate metabolism through multiple intracellular signaling pathways, including cAMP/PKA, PI3K/Akt, and SIRT1-mediated cascades, influencing glucose uptake, mitochondrial function, and inflammatory responses [82], which may contribute to interactions between GLP-1RA therapy and skeletal muscle metabolism, potentially affecting muscle metabolism and quality

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Study reveals how fast weight returns after ending GLP-1 drugs Weight loss drugs like Ozempic and Wegovy have had a meteoric rise in recent years, but how fast does the weight return after stopping treatment