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From the red carpets of Hollywood to NHS clinics across the UK, this new class of medicines, known as GLP-1 receptor agonists, is rapidly changing the way we approach obesity
The Food and Drug Administration says in its safety profiles of drugs like Ozempic and Wegovy that they should not be taken during pregnancy, noting there is "insufficient data" available
Semaglutides clinical efficacy profile , characterised by HbA1c reductions of 1.52.0% and body weight reductions of 1015% with subcutaneous dosing and up to 17% with the higher-dose Wegovy formulation , represents the highest efficacy achieved by any selective GLP-1R agonist and substantially exceeds the outcomes achieved with liraglutide, exenatide, and earlier GLP-1R agonists
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