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Evidence that systemic NAD pools undergo inter-organ redistribution and dynamic turnover [96, 107, 126] supports the view that redox stability reflects flux kinetics rather than static metabolite concentrations
The rationale is straightforward: a 120kg individual has significantly more tissue volume for the peptide to distribute through than a 70kg individual, which affects both the effective concentration at receptor sites and the perceived intensity of side effects
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Use an alcohol pad to clean the top of the vial for 30 seconds
Item 4 (whether a comprehensive literature search strategy was used) was also frequently rated as partially met, as most meta-analyses did not clarify whether grey literature was searched when appropriate or whether experts in the field were consulted
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