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Glutathione S transferases class Pi and Mi and their significance in oncology [PMID: 28665283] Laboratory literature summary: Glutathione S transferases class Pi and Mi and their significance in oncology
Further, AMPK has been reported to be an upstream activator of NRF2 85
Sikiri, P., Petek, M., Rucman, R., Seiwerth, S., Grabarevi, Z., Rotkvi, I., Turkovi, B., Jagi, V., Mildner, B., & Duvnjak, M
Collectively, these recent contributions argue that future GSH-centric redox sensing and nanomedical approaches should (i) incorporate organelle targeting (especially mitochondria) to exploit subcellular redox heterogeneity, (ii) embed analyte-responsive activation into both therapeutic and imaging components, (iii) combine biochemical sensing with optical or thermal engineering for spatiotemporal control, and (iv) favor clinically translatable carriers (e.g., PLGA) for delivery
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