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However, numerous studies have shown that, aside from its anti-protease properties, AAT has anti-inflammatory and immune regulatory functions, and some of these functions seem to be independent of the anti-protease activities

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For a number of years, while the patent is in effect, no one can manufacture and sell that compound except the company that invented it unless it is in shortage

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Previous study reported that although Nrf2 deficiency may reduce trabecular bone mass, compensatory bone remodeling or individual differences could lead to higher trabecular bone in some KO mice 53 , which also highlighted the functional diversity of Nrf2