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This is big news, and will likely pressure insurersand the governmentto widen its Wegovy coverage
A meta-analysis of 21 clinical studies showed a weighted mean difference in body weight of 2.9 kg (95% confidence interval [CI] 3.6 to 2.2) with the maximum dose of each one of the GLP-1RAs [43]
There was also a dose-response effect on the reduction in emptying rate
Early research in animals suggests that GLP-1 drugs may enhance the effectiveness of some immunotherapies
Journal of women's health (2002), 28(5), 705711
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![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)
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