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At 72 weeks, all doses (6 mg, 12 mg, 36 mg) met the primary endpoint of superior body weight reduction versus placebo and achieved key secondary goals including 10%, 15%, and 20% weight loss and reduced waist circumference
For instance, insulin doses may need to be reduced by 10 to 20 percent, depending on baseline control and risk factors
References Younossi ZM, Stepanova M, Al Shabeeb R, Eberly KE, Shah D, Nguyen V, et al
10.2337/db10-1740 5 BahneE.SunE
Use of these medications is also associated with improvements in mental health and quality of life
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