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Upon reperfusion, the abrupt ROS burst and the release of DAMPs recruit circulating monocytes and promote their differentiation into pro-inflammatory M1 macrophages
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4a, b), which was not affected by the inclusion of TNF in the media (Fig
In the multivariate analysis, l-carnitine administration (OR 3.51, 95% CI 1.239.99, p = 0.019) and baseline NIRS data of 0.07 mMmm (OR 5.21, 95% CI 1.6916.0, p = 0.0041) were found as significant independent factors (Table 3)
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