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While true deficiency can cause serious problems, many people end up taking doses far higher than they need

Adenosylcobalamin: Like methylcobalamin, adenosylcobalamin is an active form of B12

UK guidance recommends hydroxocobalamin 1mg intramuscularly with dosing frequency determined by presence of neurological involvement

Heres a general guide: For the first treatment: 1 mL (1000 mcg) given as an intramuscular shot once a week for 4-6 weeks

Reconstitution requires bacteriostatic water (water containing 0.9% benzyl alcohol as a preservative): Standard Reconstitution: Add 2 mL of bacteriostatic water to a 5 mg vial, creating a concentration of 2.5 mg/mL (2,500 mcg/mL)