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Reported Risks and Side Effects Gastrointestinal Issues: These may include nausea, vomiting, bloating, diarrhea, constipation, and slowed gastric emptying, which can sometimes lead to discomfort or changes in appetite

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Patients should be advised to stop tirzepatide and seek urgent medical attention if they experience severe, persistent abdominal pain radiating to the back, as pancreatitis can lead to systemic complications, including acute kidney injury

Roshini Raj, a New York gastroenterologist, said on TODAY