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Around 70% of hepatocytes were lost early after transplantation due to neutrophil and macrophage/monocyte infiltration elicited by complement activation and cytokine release ( Complement system initializes innate immune system activation and shares a crosstalk with coagulation system
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The peptide reduces inflammatory cytokine expression in various injury models, contributing to resolution of inflammation and transition to regenerative healing phases
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One of the standout trends fueling this shift is peptide therapy
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