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Similarly, another research examined the effect of intracerebroventricular administration of MT-II in mice and found that it increased insulin-mediated glucose disposal (uptake)

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Nidorf SM, Fiolet ATL, Mosterd A et al (2020) Colchicine in patients with chronic coronary disease

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MT2 also interacts with other melanocortin receptors involved in sexual function and metabolism, contributing to its libido-enhancing and appetite-suppressing effects