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Ideal candidates might include those who: Have documented binge eating episodes causing significant distress Meet BMI criteria for weight management medications Have not responded adequately to psychological interventions (such as cognitive behavioural therapy) Do not have contraindications to GLP-1 therapy Understand the off-label nature of this indication UK SmPCs for GLP-1 medications note findings of thyroid C-cell tumours in rodent studies, though the relevance to humans remains uncertain
Theriogenology 105, 150157
If you are taking semaglutide and notice a significant decrease in urine output, dark-colored urine, or swelling in the legs and feet, contact your healthcare provider promptly
It is not intended or approved for human or veterinary use
Step 5: Provider-directed evaluation If constipation persists despite the steps above for more than 4 weeks, provider evaluation is appropriate
