Co-agonism showed, on murine models, the capability to improve insulin secretion and sensitivity in a weight-dependent and weight-independent manner, probably through its action on nutrient metabolism (49, 50), preventing their accumulation and thus making these organs actively involved in metabolism with an improvement in insulin sensitivity and WL, yielding long-lasting effects
GLP-1 therapies are marking the start of a new generation of targeted medications that reshape how we approach metabolic health
This reflects the massmarket scale of obesity and diabetes, where oral options could materially expand access, persistence, and earlier therapy initiation or continuation of treatment for patients moving from injectable to orals, Campbell said
Chief Financial Officer Yemi Okupe told investors the decline in gross margin was due to scaling its GLP-1 offerings and strategic pricing for those products
Endocrinologists turn to ophthalmologists to discuss whether to start certain patients on the drug