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The comparison between germ-free and conventionally raised mice through whole-genome bisulfite sequencing revealed that the presence of commensal microbiota in the intestinal epithelium influences TET2/3-dependent DNA methylation changes at the regulatory elements of specific genes, which helps in the maintenance of gut balance
Jorge RE, Acion L, Starkstein SE, Magnotta V
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10.1126/science.1170803 Science 60 NicolaidesN
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