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Medicine 96 , e8952 (2017)
For structures in complex with ligands, a strong positive electron density was consistently detected at the binding sites of evolved sensors, which fit with the target isoquinoline chemical structures (Supplementary Fig
Rama Rao Jr
Nanocarriers offer programmable features, including pH-sensitive matrices like alginate-chitosan for gastric resistance and colonic release, mucoadhesive coatings to counter bile erosion, and enzyme-degradable polymers for microbiome-activated delivery
(2011) Pyridoxal-5-phosphate-dependent enzymes involved in biotin biosynthesis: structure, reaction mechanism and inhibition, Biochim
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