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As these dosing schedules are recommended off-label, no clinical trials have been conducted on biweekly dosing of semaglutide, and long-term safety remains unknown
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A patient whose genetic profile suggests slower GLP-1 receptor turnover may stabilize at 0.5 mg long-term, while another person reaches therapeutic benefit at 2.4 mg without adverse events
Weight regain after stopping One thing to plan for is the likelihood of regaining some weight after stopping the medication
Presented for research literature review only Wulff BS et al
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