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Based on current clinical evidence, tirzepatide (Zepbound) produces the highest average weight loss, followed by semaglutide (Wegovy), and then liraglutide (Saxenda)
The placenta has to provide the fetus with the nutrients and to serve to eliminate waste products of fetal metabolism
These medications mimic a hormone that helps control appetite and blood sugar levels
Appa, Y., Yohn, J., Stern, R., & Mehta, R
A meta-analysis of seven SURPASS clinical trials in participants with T2DM showed the hazard ratios comparing tirzepatide versus controls of 0.80 (95% CI, 0.57 1.11) for 4-MACE, 0.90 (95% CI, 0.50 1.61) for cardiovascular death, and 0.80 (95% CI, 0.51 1.25) for all-cause mortality (264)
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