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First, the biodistribution of the liposomal formulation was not directly assessed, limiting the ability to correlate regional biochemical effects with drug delivery efficiency
h Sikiric P, et al
Where insulin handles the cellular glucose disposal, amylin handles the meal-related slowdown signals appetite suppression, slowed digestion, and counter-glucagon effects
The velocity of such a ping-pong reaction with infinite true k cat and K m values can be described by the equation [ E ]/ V = 1 /[GSSCys]+ 2 /[GSH], wherein the Dalziel coefficients 1 and 2 are the slopes of secondary plots for k cat app (GSH) and k cat app (GSSCys) , respectively 39 (Supplementary Table 1)
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