So, they have to be doing all the things as we call it, the strength training, the eating enough protein, the getting sunlight, the going to bed on time, optimizing their sleep, all the things that we talk about in the metabolic world
Week 8-12: More noticeable weight loss, often reaching 5% of body weight
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Semaglutide (Ozempic, Wegovy, or compounded) activates GLP-1 receptors exclusively
Therefore, they are nowadays recommended as first line therapy in patients with T2DM and atherosclerotic cardiovascular disease to reduce events, regardless of baseline or target HbA1c and concomitant glucose-lowering medication according to the 2023 ESC guidelines for the management of cardiovascular disease in patients with diabetes [31]