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Sixty patients aged 65 and older were randomly assigned to either a loading dose regimen (daily administration for 14 days followed by weekly doses) or a regimen without a loading dose (administration every 3 days) over 90 days

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[4] A major double-blind study (17,604 participants) showed semaglutide (Wegovy) reduces major adverse cardiovascular events by 20% in adults with overweight/obesity and established cardiovascular disease, but without diabetes

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