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FIGURE 8 3.4 Evaluation of basic pharmacological profile of SR18 Taking cue from the comparative MD simulation data, SR18 was custom-synthesized and purified to homogeneity, with a purity level of 95%, as evident from the analytical HPLC profile

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Rice flour acts as a filler, ensuring consistency in each dose

NAPstar3 and 4.3 were chosen as their different K r(NADPH/NADP+) was expected to allow us to cover a broad-range of plausible cytosolic NADP redox states