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Growth Factor Activation The peptide enhances the expression and signaling of several growth factors: Fibroblast Growth Factor (FGF) stimulates fibroblast proliferation and collagen production Transforming Growth Factor-Beta (TGF-) regulates extracellular matrix remodeling Hepatocyte Growth Factor (HGF) promotes tissue regeneration and anti-apoptotic effects Collagen Synthesis and Organization BPC-157 accelerates the production of type I and type III collagenthe structural proteins that form tendons, ligaments, and the gut lining

(Frontiers in Nutrition, 2026 review)