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Some people genetically produce lower levels of natural GLP hormones, meaning they do not sense when they are full, and end up binge eating, says Kim Dennis , a psychiatrist and CEO of SunCloud Health treatment center in Chicago

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After 40 years old, when muscle mass naturally declines and nutritional requirements intensify, optimizing your diet while taking GLP-1 medications becomes critical for sustainable weight loss and overall health

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Microdosing discussions involve both medications, though semaglutide appears more frequently because it has been available longer and is more widely prescribed