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Patient initiation and maintenance of GLP-1 RAs for treatment of obesity: a narrative review and practical considerations for primary care providers
The drug (known by the brand name Ozempic in the mainstream) was initially developed to manage type 2 diabetes, but it can also be an effective option to shed some pounds
Depletion of glutathione by benzo(a)pyrene metabolites, ionomycin, thapsigargin, and phorbol myristate in human peripheral blood mononuclear cells
In a 2023 Phase 2 trial published in the New England Journal of Medicine (Jastreboff et al.), retatrutide produced 22.8% to 24.2% mean weight loss at 48 weeks at the higher doses (8 to 12 mg)
Knechtle and Nikolaidis, 2018
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