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The term is sometimes used as a research label for engineered or triple-agonist peptides that combine activity at GLP-1, GIP, and glucagon receptors in a single molecule
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Dato-DXd is also being evaluated as first-line therapy for patients with advanced/metastatic NSCLC with PD-L1 expression 50% in the phase III TROPION-Lung08 trial comparing Dato-DXd in combination with pembrolizumab vs
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