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In healthy, unstressed cells, the GSH/GSSG ratio exceeds 100:1 a ratio that serves as a fundamental index of cellular redox status in oxidative stress research
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Drawing upon the known property of exosomes to targetedly deliver bioactive molecules, we raise a speculative hypothesis: exosomes released by damaged endothelium might have the theoretical capacity to induce secondary cuproptosis responses in the vascular microenvironment, potentially by encapsulating abnormal copper transporters or cytotoxic lipoylated protein aggregates
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Introduction (S.W.J
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