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Deficiency is widespread in the UK due to limited sunlight exposure, and is particularly prevalent in those with chronic illness, darker skin tones, or conditions affecting fat absorption
Oral B12 supplements require intrinsic factor a glycoprotein produced in the stomach to be absorbed through the ileum
Basic local alignment search tool (in Eng)
Vitamin B-6 (pyridoxine)
Its mechanism is purely metabolic: it directly targets lipid metabolism via inhibition of NNMT and restoration of cellular NAD+
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